Parkinsonism in alcohol withdrawal: A follow‐up study
Identifieur interne : 006289 ( Main/Exploration ); précédent : 006288; suivant : 006290Parkinsonism in alcohol withdrawal: A follow‐up study
Auteurs : Shandling [Canada] ; P. L. Carlen [Canada] ; A. E. Lang [Canada]Source :
- Movement Disorders [ 0885-3185 ] ; 1990.
English descriptors
- KwdEn :
- MESH :
- complications : Alcoholism.
- etiology : Parkinson Disease.
- physiopathology : Substance Withdrawal Syndrome.
- Acute Disease, Aged, Female, Follow-Up Studies, Humans, Male, Middle Aged.
Abstract
Transient parkinsonism associated with alcohol intake and withdrawal has previously been described. We followed‐up three patients with acute alcohol withdrawal‐induced parkinsonism 9–11 years after their initial presentation. None showed any evidence of parkinsonism at follow‐up. This suggests that withdrawal‐induced parkinsonism is caused by a completely reversible abnormality in nigrostriatal dopamine transmission, which is unaccompanied by underlying nigral degeneration, as we had previously hypothesized.
Url:
DOI: 10.1002/mds.870050109
Affiliations:
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Le document en format XML
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<series><title level="j">Movement Disorders</title>
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<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (etiology)</term>
<term>Parkinsonism</term>
<term>Substance Withdrawal Syndrome (physiopathology)</term>
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<term>Male</term>
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<front><div type="abstract" xml:lang="en">Transient parkinsonism associated with alcohol intake and withdrawal has previously been described. We followed‐up three patients with acute alcohol withdrawal‐induced parkinsonism 9–11 years after their initial presentation. None showed any evidence of parkinsonism at follow‐up. This suggests that withdrawal‐induced parkinsonism is caused by a completely reversible abnormality in nigrostriatal dopamine transmission, which is unaccompanied by underlying nigral degeneration, as we had previously hypothesized.</div>
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